Erhaltungstherapie mit Methadontabletten - Eine Übersicht

Erhaltungstherapie mit Methadontabletten - Eine Übersicht

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For more information on the possible side effects of methadone, or tips on how to deal with a troubling side effect, talk with your doctor or pharmacist.

Published animal data have reported increased neonatal mortality in the offspring of male rodents that were treated with methadone prior to mating. In these studies, the female rodents were not treated with methadone, indicating paternally-mediated developmental toxicity. Specifically, methadone administered to the male rat prior to mating with methadone-naive females resulted rein decreased weight gain rein progeny after weaning. The male progeny demonstrated reduced thymus weights, whereas the female progeny demonstrated increased adrenal weights. Further, behavioral testing of these male and female progeny revealed significant differences rein behavioral tests compared to control animals, suggesting that paternal methadone exposure can produce physiological and behavioral changes hinein progeny in this model. Other animal studies have reported that perinatal exposure to opioids including methadone alters neuronal development and behavior in the offspring. Perinatal methadone exposure hinein rats has been linked to alterations in learning ability, motor activity, thermal regulation, nociceptive responses and sensitivity to drugs.

For women who are breastfeeding: Methadone may pass into breast milk and may cause side effects hinein a child Weltgesundheitsorganisation is breastfed.

A prescription for this medication isn’t refillable. You or your pharmacy will Methadontabletten online kaufen have to contact your doctor for a new prescription if you need this medication refilled.

You may need to show airport staff the pharmacy Wortmarke for your medication. Always carry the Urfassung prescription-labeled container with you.

When starting treatment with methadone hydrochloride tablets for narcotic drug dependence, you should be aware that your dose of methadone will “hold” for longer periods of time as treatment goes on.

The administration of opioids may obscure the diagnosis or clinical course of patients with acute abdominal conditions.

are allergic to methadone or anything else rein methadone hydrochloride tablets. See the end of this leaflet for a complete Trick of ingredients.

There may Beryllium new information. This leaflet does not take the place of talking with your doctor about your medical condition or your treatment. Share the important information rein this leaflet with members of your household.

Laxatives. Taking these drugs together can change your electrolyte levels. This can cause heart rhythm problems.

Patients should Beryllium instructed to keep methadone rein a secure place out of the reach of children and other household members. Accidental or deliberate ingestion by a child may cause respiratory depression that can result hinein death.

Typically, your doctor will start you on a low dosage and adjust it over time to reach the dosage that’s right for you. They’ll ultimately prescribe the smallest dosage that provides the desired effect.

Clinical studies of methadone did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently compared to younger subjects. Other reported clinical experience has not identified differences in responses between elderly and younger patients.

Laboratory studies, both in vivo and hinein vitro, have demonstrated that methadone inhibits cardiac potassium channels and prolongs the QT interval. Cases of QT interval prolongation and serious arrhythmia (torsades de pointes) have been observed during treatment with methadone. These cases appear to be more commonly associated with, but not limited to, higher dose treatment (> 200 Magnesium/day). Most cases involve patients being treated for pain with large, multiple daily doses of methadone, although cases have been reported hinein patients receiving doses commonly used for maintenance treatment of opioid addiction.